Medina County Ohio Real Estate ________________________________________________________________________________ Medina County Ohio is located in north central Ohio and is the seventeenth most populous county in the state, based on 2000 census figures. Medina County is currently one of the top ten fastest growing counties in Ohio.  Medina County comprises approximately 425 square miles.  Medina County consists of the following cities: Brunswick, Medina, Rittman, and Wadsworth.